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How Exactly Does Paracetamol Work?
Paracetamol is a common over-the-counter pain reliever that is used globally, so imagine our shock at discovering that no one completely understands its exact mechanism in the body. We know that it reduces fever and alleviates pain, but unlike other painkillers like NSAIDs, it doesn’t work by reducing inflammation.
The prevailing understanding is that paracetamol acts directly on the brain, possibly inhibiting an enzyme involved in pain and temperature regulation. Interestingly, it might also influence the endocannabinoid system, which affects pain perception. However, these explanations don’t fully account for all of its effects and variations in individual responses.
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